Messi had a goal and an assist before leaving the game in the 50th minute.

Inter Miami advanced to the CONCACAF Champions Cup quarterfinals with the win and 5-3 advantage in aggregate goals in the total-goals series.

Martino said Messi will likely be rested for Inter Miami’s MLS match against D.C. United on Saturday as further precaution.

Inter Miami forward Lionel Messi races ahead of Nashville SC midfielder Anibal Godoy during the first half of a CONCACAF Champions Cup soccer match Wednesday, March 13, 2024, in Fort Lauderdale, Fla.

Messi had played every minute of the season before being rested in Sunday’s 3-2 loss to Montreal.

He was injured late in the first leg of the CONCACAF Champions Cup round of 16 at Nashville last Thursday. Messi went down late in regulation of that game when Nashville defender Lukas MacNaughton stepped on his calf. A trainer checked on Messi, who writhed in pain on the pitch, but he remained in the game.

He had been listed as questionable with a shin injury entering Sunday´s game against Montreal.

Martino said Wednesday that Messi will undergo tests, and the team will evaluate from there.

Inter Miami is currently amid a busy March that includes seven matches – four of which have come in a 10-day span. Messi is expected to join the Argentinian national team in a pair of Copa America warm-up matches on March 22 and 26.

Inter Miami forward Lionel Messi is tripped by the Nashville SC defense during the first half of a CONCACAF Champions Cup soccer match, Wednesday, March 13, 2024, in Fort Lauderdale, Fla.

Inter Miami forward Lionel Messi dribbles past Nashville SC forward Jacob Shaffelburg during the first half of a CONCACAF Champions Cup soccer match, Wednesday, March 13, 2024, in Fort Lauderdale, Fla.