The Aquaman star, 44, and Wonder Woman actress, 38, were seen hard at work shooting scenes for the new film.
The film, directed by Julian Schnabel, is currently in early production as character details are yet to be revealed.
Jason was dressed in a white tuxedo with a huge white cowboy hat as he got stuck into character on set.
While the Israeli actress was dressed in a white midi skirt and a green top as she was pictured aiming a gun at Jason during scenes.
New stint: Jason Momoa, 44, and Gal Gadot, 38, were pictured filming in character for the upcoming movie In The Hand Of Dante in Venice on Friday
Upcoming: The Wonder Woman actress was seen hard at work shooting scenes for the new film
Scenes saw Jason hold his arms up in the air before getting down on his knees to shoot fake bullets into the distance.
Johnny Depp, who purchased the film rights Nick Tosches novel in 2008, has opted out of featuring in the movie.
Instead, Julian has decided to make the film adaptation starring Oscar Isaac in place of Johnny.
The film follows the story of a priest who has discovered the rarest and most valuable art object ever found.
As well as Jason’s role in the film, he is set to co-star with Dave Bautista in an upcoming comedy action movie, with the same director as Blue Beetle.
Angel Manuel Soto is leading the production for The Wrecking Crew, with deals for the two actors agreed prior to the acting union strikes and the script written before the writers’ strikes.
The writer and actors’ strikes began in June and July respectively.
Plot details about the new comedy are being kept quiet, but it is expected to be a ‘buddy action comedy’.
Tense: The Aquaman star was dressed in a white tuxedo with a huge white cowboy hat as he got stuck into character on set
Shoot off: Scenes saw Jason hold his arms up in the air before getting down on his knees to shoot fake bullets into the distance
New movie: Jason was pictured surrendering to Gal in early scenes for the upcoming film
Production set: The film, directed by Julian Schnabel, is currently in early production as character details are yet to be revealed
Early production: Johnny Depp , who purchased the film rights Nick Tosches novel in 2008, has opted out of featuring in the movie
Filming: Jason appeared to have held a man hostage in a scene, dressed in his cow-boy attire on set
Taking a break: The crew and Gal were spotted chatting on set for the new production
This comes almost two years after Bautista tweeted that the pair should star in a ‘buddy cop’ movie together.
The Guardians Of The Galaxy star said: ‘Just going to throw this out into the atmosphere and see what happens. Here we go…
‘Me and Momoa in a Lethal Weapon type buddy cop movie directed by David Leitch. Ok! There it is. Now we wait.’
The two met while working together on sci-fi action series See, and also starred alongside one another in Dune in 2021.
Momoa later shared his co-star’s sentiment, speaking on The Late Late Show With James Corden.
He said: ‘We love each other, you know, obviously we met on See, we’re on Dune together, so I said “absolutely.”
‘It sells itself. Dave loves wearing speedos. I love wearing board shorts. Both of us with our shirts off. Buddy cop film. He’ll be grumpy, I’ll be charming. Boom. It sells itself.’
About time: Bautista (pictured in January) tweeted the idea of he and Momoa starring alongside each other in a ‘buddy cop’ movie in 2021